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TLS Online TPP Program

#Question id: 12497

In this pedigree A and B represent alleles at a marker locus closely linked to the disease locus. Affected individuals are shown as shaded. The disease status in III 1 is unknown. Which of the following is correct?

#Unit 8. Inheritance Biology
  1. The probable pattern of inheritance shown by the disease in this family is autosomal recessive.
  2. If recombination does not occur the probability that III 1 will be affected if she has an AB marker genotype is 1.
  3. If recombination does not occur, the probability that III 1 will be affected if she has a BB marker genotype is 1.
  4. If the recombination fraction between the disease and marker loci equals 0.04, the probability that III 1 will be affected if she inherits an AB marker genotype equals 0.96.

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TLS Online TPP Program

#Question id: 12561

#Unit 7. System Physiology – Animal

Given the following measurements, calculate the filtration fraction: glomerular capillary hydrostatic pressure = 50 mm Hg; Bowman’s space hydrostatic pressure = 15 mm Hg; colloid osmotic
pressure in the glomerular capillaries = 30 mm Hg; glomerular capillary filtration coefficient (Kf) = 12 ml/min/mm Hg; and renal plasma flow = 400 ml/min.
TLS Online TPP Program

#Question id: 12658

#Unit 7. System Physiology – Animal

In a person on a high (200 mmol/day) potassium diet, which part of the nephron would be expected to secrete the most potassium?
TLS Online TPP Program

#Question id: 12659

#Unit 7. System Physiology – Animal

 Which of the following would tend to decrease plasma potassium concentration by causing a shift of potassium from the extracellular fluid into the cells?
TLS Online TPP Program

#Question id: 12697

#Unit 7. System Physiology – Animal

The following test results were obtained: urine flow rate = 2.0 ml/min; urine inulin concentration = 60 mg/ml; plasma inulin concentration = 2 mg/ml; urine potassium concentration = 20 μmol/ml; plasma potassium concentration = 4.0 μmol/ml; urine osmolarity = 150 mOsm/L; and plasma osmolarity = 300 mOsm/L. What is the approximate GFR?
TLS Online TPP Program

#Question id: 12698

#Unit 7. System Physiology – Animal

The following test results were obtained: urine flow rate = 2.0 ml/min; urine inulin concentration = 60 mg/ml; plasma inulin concentration = 2 mg/ml; urine potassium concentration = 20 μmol/ml; plasma potassium concentration = 4.0 μmol/ml; urine osmolarity = 150 mOsm/L; and plasma osmolarity = 300 mOsm/L. What is the net potassium reabsorption rate?
TLS Online TPP Program

#Question id: 12699

#Unit 7. System Physiology – Animal

The following test results were obtained: urine flow rate = 2.0 ml/min; urine inulin concentration = 60 mg/ml; plasma inulin concentration = 2 mg/ml; urine potassium concentration = 20 μmol/ml; plasma potassium concentration = 4.0 μmol/ml; urine osmolarity = 150 mOsm/L; and plasma osmolarity = 300 mOsm/L. What is the free water clearance rate?