Practice Questions

TLS Online TPP Program

#Question id: 12570

Extinction is a natural phenomenon. It is estimated that 99% of all species that ever lived are now extinct. Why then do we say that we are now in a biodiversity crisis?

#Unit 10. Ecological Principles

Humans are ethically responsible for protecting endangered species.
Scientists have finally identified most of the species on earth and are thus able to Quantify the number of species becoming extinct.
The current rate of extinction is high and human activities threaten biodiversity at all levels.
Humans have greater medical needs than at any other time in history, and many potential medicinal compounds are being lost as plant species become extinct.

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TLS Online TPP Program

#Question id: 34172

#Unit 3. Fundamental Processes

Frameshifts occur when an extra nucleotide is inserted or omitted. Which of sequence and property is most sensitive combination for the frameshift to occur

TLS Online TPP Program

#Question id: 34173

#Unit 3. Fundamental Processes

The 3’–5’ exonucleolytic activity is found in which subunit of bacterial DNA Polymerase III

TLS Online TPP Program

#Question id: 34174

#Unit 3. Fundamental Processes

Once bound to a primer:template junction, DNA polymerase interacts tightly with much of the double stranded portion of the DNA by

TLS Online TPP Program

#Question id: 34175

#Unit 3. Fundamental Processes

A. For processive DNA synthesis, proofreading occurs without releasing the DNA from the polymerase

B. When a mismatched base pair is present in the polymerase active site, the primer:template junction is destabilize

C. The DNA polymerase active site binds such a mismatched template poorly, but the exonuclease active site has a 10-fold higher affinity.

D. The incorrect nucleotide is removed by the 5’-3’-exonuclease nuclease activity

Choose true and false

TLS Online TPP Program

#Question id: 34176

#Unit 3. Fundamental Processes

A. The lagging strand must be synthesized in the form of Okazaki fragments.

B. Both strands are synthesized discontinuously.

C. Not all of the fragment population represents bona fide Okazaki fragments; some are pseudofragments

D. Primers start with the sequence pppAG positioned opposite the sequence 3’–GTC-5’ in the template

Choose true and false

TLS Online TPP Program

#Question id: 34177

#Unit 3. Fundamental Processes

Which of the following combination of the statements regarding polA mutants is correct

A. fail to join their Okazaki fragments

B. fail to removes the RNA primer

C. fail to removes the mismatch errors

D. fail to synthesis Okazaki fragments