TLS Online TPP Program

#Question id: 3624


To carry out a complementation test, parents that are homozygous for different mutations are crossed, producing offspring that mutant phenotype, it is due to

#Part-B Specialized Branches in Biotechnology
  1. The mutations are occur at the same locus

  2. The mutations are occur at different locus

  3. synergistic effect of two different non allelic gene

  4. Linkage

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TLS Online TPP Program

#Question id: 12488

#Part-A Aptitude & General Biotechnology

Retinoblastoma usually occurs as a sporadic event but in around 10% of cases there is a positive family history due to autosomal dominant inheritance. In these families the penetrance is approximately 80% (= 0.8). A woman with retinoblastoma, whose father and grandfather were also affected, has an unaffected partner with no relevant family history. Which of the following is correct regarding their children?

TLS Online TPP Program

#Question id: 12489

#Part-A Aptitude & General Biotechnology

Achondroplasia shows autosomal dominant inheritance with complete penetrance. A man with achondroplasia has an unaffected partner of normal height. Their first two children are not affected. Which of the following is correct?

TLS Online TPP Program

#Question id: 12490

#Part-A Aptitude & General Biotechnology

Tay-Sachs disease shows autosomal recessive inheritance. Parents of a newly diagnosed affected child are referred for genetic counselling. It would be correct to tell them that:

TLS Online TPP Program

#Question id: 12490

#Part-B Specialized Branches in Biotechnology

Tay-Sachs disease shows autosomal recessive inheritance. Parents of a newly diagnosed affected child are referred for genetic counselling. It would be correct to tell them that:

TLS Online TPP Program

#Question id: 12491

#Part-A Aptitude & General Biotechnology

Phenylketonuria shows autosomal recessive inheritance with an incidence of 1 in 10000. Assume that the population is in Hardy-Weinberg equilibrium. Which of the following is correct?

TLS Online TPP Program

#Question id: 12491

#Part-B Specialized Branches in Biotechnology

Phenylketonuria shows autosomal recessive inheritance with an incidence of 1 in 10000. Assume that the population is in Hardy-Weinberg equilibrium. Which of the following is correct?