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Class III MHC genes encode several different proteins, some with immune functions, include the complement components C4, C2, and factor B, TNF-α and Lymphotoxin-α [TNF- α]. 

#Section 2: General Biology #Major histocompatibility complex #Part B Pointers
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The heavy chain is then expressed on the cell surface in combination with the surrogate light chain, which is made up of VpreB and λ5. 

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B- cell maturation

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T1 and T2 Transitional B Cells

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T1 cells are mIgMhi, mIgD -/lo, CD21-, CD23-, CD24+, and CD93+. 
T2 cells differ from T1 cells in having higher levels of mIgD and in expressing CD21 and CD23. 

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