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TLS Online TPP Program

#Id: 2229

The Birth of a Gene - Duplication is the most common way that new genes arise in eukaryotes. 

#Section 3: Genetics, Cellular and Molecular Biology #Origin of new genes and proteins #Part B Pointers
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TLS Online TPP Program

#Id: 8605

#Section 3: Genetics, Cellular and Molecular Biology

S phase Cyclin–CDKs
In human - cyclin A-CDK 2 
In budding yeast - CIb 5/6-Cdc 28
TLS Online TPP Program

#Id: 8606

#Section 3: Genetics, Cellular and Molecular Biology

M phase Cyclin–CDKs
In human - cyclin A-CDK 1
cyclin B-CDK 1
In budding yeast - CIb 1/2/3/4-Cdc 28
TLS Online TPP Program

#Id: 8607

#Section 3: Genetics, Cellular and Molecular Biology

Cdk1 
=Cdc2 (vertebrates and fission yeast)
= Cdc28  (budding yeast)
TLS Online TPP Program

#Id: 8608

#Section 3: Genetics, Cellular and Molecular Biology

There are three D cyclins in mammals:
cyclins D1, D2, and D3
TLS Online TPP Program

#Id: 8609

#Section 3: Genetics, Cellular and Molecular Biology

In free CDK2, the A-loop blocks access of protein substrates to the γ phosphate of the bound ATP.
TLS Online TPP Program

#Id: 8610

#Section 3: Genetics, Cellular and Molecular Biology