Unassembled or misfolded proteins in the ER are often transported back to the cytosol, where they are degraded in the ubiquitin-proteasome pathway

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#Section 3: Genetics, Cellular and Molecular Biology

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#Section 3: Genetics, Cellular and Molecular Biology

No matter how it is born, a new gene starts its life as a single copy in the population.

As with any new mutation, by far the most likely outcome is that it will be lost by random drift or selection over the next few generations

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#Section 2: General Biology

Fingolimod—a Sphingosine-1-P Mimic Is an Oral Drug for Multiple Sclerosis

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#Id: 10379

#Section 2: General Biology

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#Id: 9194

#Section 3: Genetics, Cellular and Molecular Biology

Hitchhiking

An important consequence of linkage disequilibrium is hitchhiking. This happens when an allele at  one locus spreads by natural selection acting on a second locus that is in linkage disequilibrium with  the first.