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Diphosphatidylglycerol or Cardiolipin are synthesized within the mitochondria

#Section 2: General Biology #Lipid #Part B Pointers
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#Section 2: General Biology

Class II MHC glycoproteins expressed predominantly on pAPCs, where they primarily present exogenous antigenic peptides to CD4+ T cells.


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#Section 2: General Biology

Class III MHC genes encode several different proteins, some with immune functions, include the complement components C4, C2, and factor B, TNF-α and Lymphotoxin-α [TNF- α]. 

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#Section 2: General Biology

HLA-G

These are present on fetal cells at the maternal-fetal interface and are credited with inhibiting rejection by maternal CD8+ T cells by protecting the fetus from identification as foreign.

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#Section 2: General Biology

A given MHC molecule can bind numerous different peptides, and some peptides can bind to several different MHC molecules. Because of this MHC molecule is often referred to as “promiscuous”.

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MHC-Peptide Interaction


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