The amino group at C-2 bears a fatty acid in amide linkage.

The fatty acid is usually saturated or monounsaturated, with 16, 18, 22, or 24 carbon atoms.

Ceramide is the parent compound for this group.

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#Section 2: General Biology

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#Id: 10343

#Section 2: General Biology

The heavy chain is then expressed on the cell surface in combination with the surrogate light chain, which is made up of VpreB and λ5. 

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B- cell maturation

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#Section 2: General Biology

T1 and T2 Transitional B Cells

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T1 cells are mIgMhi, mIgD -/lo, CD21-, CD23-, CD24+, and CD93+. 

T2 cells differ from T1 cells in having higher levels of mIgD and in expressing CD21 and CD23. 

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#Section 2: General Biology

Transitional B cells bound for a follicular fate undergo positive and negative selection in the spleen.