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TLS Online TPP Program

#Id: 8412

Binding of Ca2+ ions to TN-C
triggers movement of TM to a new position on the filament, thereby exposing the myosin-binding sites on actin.

#Section 3: Genetics, Cellular and Molecular Biology #Myosin & Muscle Contraction #Part B Pointers
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TLS Online TPP Program

#Id: 8335

#Section 3: Genetics, Cellular and Molecular Biology

TLS Online TPP Program

#Id: 8334

#Section 3: Genetics, Cellular and Molecular Biology

Phalloidin 
isolated from Amanita phalloides, binds at the interface between subunits in F-actin, locking adjacent subunits together and preventing depolymerization.
TLS Online TPP Program

#Id: 8333

#Section 3: Genetics, Cellular and Molecular Biology

Jasplakinolide,
a sponge toxin, enhances nucleation by binding and stabilizing actin dimers and lowering the Cc.
TLS Online TPP Program

#Id: 8332

#Section 3: Genetics, Cellular and Molecular Biology

Latrunculin, 
a toxin secreted by sponges, binds and sequesters G-actin
TLS Online TPP Program

#Id: 8331

#Section 3: Genetics, Cellular and Molecular Biology

Cytochalasin D, 
a fungal alkaloid, depolymerizes actin filaments by binding to the (+) end of F-actin.
TLS Online TPP Program

#Id: 8330

#Section 3: Genetics, Cellular and Molecular Biology