Human SCF complexes contain: 

Three core components - Cul1 subunit, RBX1, Skp1 

and a substrate-targeting F-box protein

TLS Online TPP Program

#Id: 8643

#Section 3: Genetics, Cellular and Molecular Biology

When E2Fs are bound to Rb, not only are they transcriptionally inactive, but they also function to repress transcription by recruiting chromatin-modifying enzymes that promote deacetylation and methylation of specific histone lysines.

TLS Online TPP Program

#Id: 8199

#Section 3: Genetics, Cellular and Molecular Biology

Lysosomes contain about 40 types of hydrolytic enzymes, All are acid hydrolases, work best at acidic pH including: proteases, nucleases, glycosidases, lipases, phospholipases, phosphatases, and sulfatases.

TLS Online TPP Program

#Id: 8140

#Section 3: Genetics, Cellular and Molecular Biology

Anterograde transport

COPII vesicles = ER to Golgi

TLS Online TPP Program

#Id: 8608

#Section 3: Genetics, Cellular and Molecular Biology

There are three D cyclins in mammals:

cyclins D1, D2, and D3

TLS Online TPP Program

#Id: 7951

#Section 3: Genetics, Cellular and Molecular Biology

First sugar residue is attached to dolichol by a high-energy pyrophosphate linkage & the other sugars are added by glycosidic bonds