Cohesins establish linkages between the replicated DNA molecules, which are essential for their accurate segregation later in the cell cycle. This linking mechanism is coupled to DNA replication.

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#Id: 10349

#Section 2: General Biology

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#Section 2: General Biology

B cells migrate to the lymphoid follicles. They are directed there by chemokine interactions between CXCL13, which is secreted by follicular dendritic cells (FDCs).

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#Section 2: General Biology

B-cell survival in the follicle is dependent on access to the TNF-family member cytokine B-cell activation factor (BAFF), otherwise known as B lymphocyte survival factor (BLyS), which is secreted by the FDCs.

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#Id: 10352

#Section 2: General Biology

B-cell activation

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#Section 2: General Biology

TLS Online TPP Program

#Id: 10358

#Section 2: General Biology

T-dependent response

Recognition of protein antigens and requires the participation of CD4 helper T cells