Pin1 and Plk1 modify and phosphorylate Cdc25C to stimulate its phosphatase activity

TLS Online TPP Program

#Id: 8878

#Section 3: Genetics, Cellular and Molecular Biology

At the same time that Cdc25C is being activated, mitotic CDKs and Plk1 phosphorylate Wee1, which targets it for destruction through a phosphobinding SCF protein-ubiquitin ligase. This forms positive feedback loop 2

TLS Online TPP Program

#Id: 8958

#Section 3: Genetics, Cellular and Molecular Biology

Genetic exchange also happens between distantly related organisms by horizontal gene transfer, or HGT.

HGT is particularly important to prokarytotes and is the most common way by which they acquire new genes.

TLS Online TPP Program

#Id: 8312

#Section 3: Genetics, Cellular and Molecular Biology

Actin exists as: 

a globular monomer -G-actin 

a filamentous polymer- F-actin

TLS Online TPP Program

#Id: 8213

#Section 3: Genetics, Cellular and Molecular Biology

Autophagy occurs in the following sequence of steps:

Induction by activation of mTOR complex 1

• Nucleation of autophagosome formation by ATG9

• Closure of the membrane cup to form autophagosome

• Fusion of the autophagosome with lysosomes, catalyzed by SNAREs.

• Digestion of the inner membrane and the lumenal contents of the autophagosome

TLS Online TPP Program

#Id: 8519

#Section 3: Genetics, Cellular and Molecular Biology