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The Aurora protein kinase family members Aurora A and Aurora B and their associated regulatory factors sense kinetochores that are not under tension and sever these microtubule attachments

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#Section 2: General Biology

HLA-G

These are present on fetal cells at the maternal-fetal interface and are credited with inhibiting rejection by maternal CD8+ T cells by protecting the fetus from identification as foreign.

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#Section 2: General Biology

A given MHC molecule can bind numerous different peptides, and some peptides can bind to several different MHC molecules. Because of this MHC molecule is often referred to as “promiscuous”.

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#Section 2: General Biology

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#Section 2: General Biology

MHC-Peptide Interaction


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#Section 2: General Biology


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#Section 2: General Biology

One individual, however, expresses only a small number of these molecules—up to six different class I molecules and 12 or more different class II molecules.


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