Hybridoma cells immobilized on surfaces of Sephadex beads are used in a packed column for production of monoclonoal antibodies (Mab). Hybridoma concentration is approximately X = 5 g/l in the bed. The flow rate of the synthetic medium and glucose concentration are Q = 2 l/h and S0 = 40 g/l, respectively. The rate constant for Mab formation is k = 1 gX/l-d. Assume that there are no diffusion limitations and glucose is the rate limiting nutrient.  Determine the volume of the packed bed for 95% glucose conversion. Bed diameter is D0 = 0.2 m. Neglect the growth of the hybridomas and assume first order kinetics. 

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#Question id: 27563

#Section 5: Bioprocess Engineering and Process Biotechnology

Match the instruments in Group 1 with their corresponding measurements in Group 2

Group 1                                                         Group 2

(P) Manometer                                              (1) Agitator speed

(Q) Rotameter                                               (2) Pressure difference

(R) Tachometer                                              (3) Cell number

(S) Haemocytometer                                     (4) Air flow rate

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#Question id: 12992

#Section 2: General Biology

α-helix changes its configurations according to the environment then

a. membrane encompassing α-helix have nonpolar residue oriented toward the membrane lipid.

b. if α-helix is found in plasm then polar residue will be oriented toward the outside.

c. if α-helix is found in plasm then nonpolar residue will be present inside the core.

d.  membrane encompassing α-helix have polar residue oriented towards the membrane lipid.

Choose incorrect statement

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#Question id: 15259

#Section 6: Plant, Animal and Microbial Biotechnology

Which media are called as general purpose media because they support the growth of many microorganisms.

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#Question id: 3801

#Section 3: Genetics, Cellular and Molecular Biology

Why should patients with xeroderma pigmentosum avoid sunlight?

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#Question id: 3610

#Section 3: Genetics, Cellular and Molecular Biology

If the genotype consists of only one type of allele. It is called