Ca2+ ions bind to sites near each hinge and prevent it

from flexing, so that the whole string of cadherin domains behaves as a rigid and slightly curved rod to generate cell–cell adhesion

TLS Online TPP Program

#Id: 8042

#XL - Q Biochemistry

A system to unambiguously describe the configurations of molecules with more than one asymmetric center was devised in 1956 by Robert Cahn, Christopher Ingold, and Vladimir Prelog. In the Cahn–Ingold– Prelog or RS system

TLS Online TPP Program

#Id: 8041

#XL - Q Biochemistry

There are two type representation of amino acid structure

1. By Fischer’s convention L and D

2. By absolute configuration RS System

TLS Online TPP Program

#Id: 8040

#XL - Q Biochemistry

TLS Online TPP Program

#Id: 8039

#XL - Q Biochemistry

Glycine at pH 2.34, where there is an equal mixture of

  the average or net positive charge is 0.5 or +1/2

TLS Online TPP Program

#Id: 8038

#XL - Q Biochemistry

His ionisation series

1------pK1-----pKr--------pKr------14

TLS Online TPP Program

#Id: 8037

#XL - Q Biochemistry

Lys & Arg have ionisation series

1------pK1-----pK2--------pKr------14