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CNK serves as a molecular scaffold platform for KSR-mediated RAF activation
 

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TLS Online TPP Program

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Inflammatory response
The response includes both localized and systemic effects, consisting of altered patterns of blood flow, an influx of phagocytic and other immune cells, removal of foreign antigens, and healing of the damaged tissue.

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#Id: 9908

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Inflammatory response

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Inflammasomes

Multiprotein complex that promotes inflammation by processing inactive precursor forms of pro-inflammatory cytokines such as IL-1 and IL-18.

Proinflammatory cytokines IL-1β, TNF, and IL-6. 

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#Id: 9910

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Inflammatory response
Inflammation may be acute (short-term effects)—for example, in response to local tissue damage.
it may be chronic (long term), contributing to conditions such as arthritis, inflammatory bowel disease, cardiovascular disease, and Type 2 diabetes.

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#Id: 9911

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Arachidonic acid and some eicosanoid derivatives

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#Id: 9912

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Cyclooxygenase-2 (COX-2)
Enzyme responsible for the formation from arachidonic acid of prostaglandins and other pro-inflammatory mediators.

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