CFTR protein contains

a di-acidic sorting signal that binds to the Sec24 subunit

of the COPII vesicle coat and is necessary for transport of

the CFTR protein out of the ER.

TLS Online TPP Program

#Id: 8166

#XL - Q Biochemistry

CFTR protein contains

a di-acidic sorting signal that binds to the Sec24 subunit

of the COPII vesicle coat and is necessary for transport of

the CFTR protein out of the ER.

TLS Online TPP Program

#Id: 9300

#XL - T Zoology

Rhodopsin has two components: 

Opsin protein, member of the GPCR A family 

11-cis-retinal light-absorbing pigment

TLS Online TPP Program

#Id: 9301

#XL - T Zoology

TLS Online TPP Program

#Id: 9302

#XL - T Zoology

11-cis-retinal covalently attached to the amino group of lysine residue 296 in the opsin protein

TLS Online TPP Program

#Id: 9303

#XL - T Zoology

The heterotrimeric G protein coupled to rhodopsin, called transducin (Gt)

TLS Online TPP Program

#Id: 9304

#XL - T Zoology

In the absence of light,  bound 11-cis-retinal locks the rhodopsin into its inactive (R) conformation

TLS Online TPP Program

#Id: 9305

#XL - T Zoology

Absorption of light causes rapid photoisomerization of the bound cis-retinal to the all-trans isomer, triggering a conformational change in opsin that activate the Gαt.