ATM and ATR, activate a triad of related protein kinases: Chk1, Chk2, and MK2

TLS Online TPP Program

#Id: 9328

#XL - T Zoology

Arrestin binds tightly to rhodopsin only when rhodopsin kinase has phosphorylated a sufficient number of C-terminal serines and threonines.

TLS Online TPP Program

#Id: 9329

#XL - T Zoology

The entire process of rhodopsin phosphorylation and its inactivation by arrestin is fast completed within 50ms. 

TLS Online TPP Program

#Id: 9330

#XL - T Zoology

Phosphorylated rhodopsin is restored to its light-sensitive state (R) during dark adaptation by a specific rhodopsin phosphatase

TLS Online TPP Program

#Id: 9331

#XL - T Zoology

In the dark, most transducin is localized to the outer segment, while most arrestin is found in other parts of the cell; in this condition, vision is most sensitive to very low light levels.

TLS Online TPP Program

#Id: 9332

#XL - T Zoology

In bright light, little transducin is found in the outer segment, and abundant arrestin is found there; in this condition,vision is relatively insensitive to small changes in light.

TLS Online TPP Program

#Id: 9333

#XL - T Zoology

An evolutionarily conserved family of receptor serine kinases - TGF-β receptor family