Polygalacturonases (PG) secreted by the fungal hyphae interact with WAK1 on plant cell wall results in the expression of plant defense proteins, including PGIPs Chitinases, glucanases, and phytoalexins to damage the fungal hyphae

TLS Online TPP Program

#Id: 8641

#XL - T Zoology

Rb binds the activation domains of a E2F transcription factors, in the cytoplasm to prevent them from turning on the genes required for cell cycle progression.

TLS Online TPP Program

#Id: 8642

#XL - T Zoology

TLS Online TPP Program

#Id: 8643

#XL - T Zoology

When E2Fs are bound to Rb, not only are they transcriptionally inactive, but they also function to repress transcription by recruiting chromatin-modifying enzymes that promote deacetylation and methylation of specific histone lysines.

TLS Online TPP Program

#Id: 8644

#XL - T Zoology

Phosphorylation on multiple sites by G1 CDKs blocks Rb from associating with E2F and promotes its export out of the nucleus.

TLS Online TPP Program

#Id: 8645

#XL - T Zoology

Rb protein regulation by G1 CDKs in mammalian cells is analogous to Whi5 regulation by Cln3-CDK in yeast.

TLS Online TPP Program

#Id: 8646

#XL - T Zoology

One of the important substrates of the G1/S phase cyclin-CDK complexes is Cdh1.