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Inflammation

Tissue response to infection or damage which serves to eliminate

Classic signs of acute inflammation are heat (calore), pain (dolore), redness (rubor), swelling (tumor), and loss of function (functio laesa).

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Resistance to leishmaniasis correlates well with the production of IFN-ϒ and the development of a TH1 response.
Strains of mice that are naturally resistant to Leishmania develop a TH1 response and produce IFN-ϒ upon infection. 

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Parasitic Worms (Helminths) Typically Generate Weak Immune Responses

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Natural immunity to helminth infections is Th2-type responses, including ILC2s, and IL-4 and IgE production.

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Immune Response Generated against Schistosoma mansoni

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Fungal disease
The barriers of innate immunity control most fungi.
Phagocytosis by neutrophils is a strong defense against most fungi

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