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TLS Online TPP Program

#Id: 9929

#XL - T Zoology #Infectious Diseases #Part B Pointers
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TLS Online TPP Program

#Id: 9916

#XL - T Zoology

Viral Infections

Virus enters a cell via a cell-surface receptor for which it has affinity and preempts cell biosynthetic machinery to replicate all components of itself, including its genome.

This genome replication step is often error prone, generating numerous mutations.
TLS Online TPP Program

#Id: 9917

#XL - T Zoology

Influenza virus binds to sialic acid residues

Rhinovirus binds to intercellular adhesion molecules (ICAMs)

Epstein Barr virus (EBV) binds to type 2 complement receptors on B cells
TLS Online TPP Program

#Id: 9918

#XL - T Zoology

Innate response elements commonly engaged by encounter with viral PAMPs, such as secretion of type I interferons, inflammasome and NK-cell activation, as well as IL-12 production.
TLS Online TPP Program

#Id: 9919

#XL - T Zoology

Mechanisms of humoral and cell-mediated immune responses
TLS Online TPP Program

#Id: 9920

#XL - T Zoology

Many Viruses Are Neutralized by Antibodies
Antibodies are particularly effective if they are localized at the site of viral entry into the body.
TLS Online TPP Program

#Id: 9921

#XL - T Zoology

Cell-Mediated Immunity against Virus
Both CD8+ TC cells and CD4+ TH1 cells are required components of the cell-mediated antiviral defense.
Activated TH1 cells produce IL-2, IFN-ϒ, and tumor necrosis factor-α.