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Rho GTPases are the “master builders” of the cell because they can activate an array of kinases and cytoskeletal binding proteins that remodel cytoskeletal elements to alter cell shape and movement

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TLS Online TPP Program

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The EGFR specifically binds EGF in a lock-and-key type of mechanism.

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The function of a growth factor-  stabilize receptor dimerization

TLS Online TPP Program

#Id: 1340

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HER1 & HER4, can form stable homodimers after binding a growth factor.

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#Id: 1341

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HER2 can signal only by forming heterodimers with ligand-bound HER1, HER3, or HER4

TLS Online TPP Program

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HER3 lacks a functional kinase domain

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#Id: 1343

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RAS is a small monomeric G-proteins.

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