Following table lists the two major forms of DNA duplexes, conformation of base attached to the sugar and the nature of major and minor grooves.

DNA duplex	Properties
(A)  A form	(i) Syn conformation of the base to sugar
(B)  B form	(ii) Anti conformation of the base to sugar
	(iii) Wide major groove
	(iv) Narrow major groove
	(v) Wide minor groove
	(vi) Narrow minor groove
	(vii) C-3’ endo sugar puckering
	(viii) C-2’ endo sugar puckering

#Question id: 23752

#Unit 1. Molecules and their Interaction Relevant to Biology

#Question id: 23751

#Unit 1. Molecules and their Interaction Relevant to Biology

#Question id: 703

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following statements concerning protein domains is true?

#Question id: 913

#Unit 1. Molecules and their Interaction Relevant to Biology

The appropriate folding of a newly translated product is essential, and continual misfolding often leads to disease, especially in vertebrates. This misfolding, particularly in the situation of prion diseases, may be due to

#Question id: 912

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following is correct about the native state of a protein

a. is unaffected by changes in temperature and pH.

b. corresponds to the highest Gibbs free energy state.

c. is determined by its primary amino acid sequence.

d. corresponds to the lowest entropic state.

#Question id: 911

#Unit 1. Molecules and their Interaction Relevant to Biology

The correct order for molecular chaperone–mediated protein folding is:

I – exchange of ATP for ADP on chaperone

II – chaperone undergoes conformational change, which affects protein folding

III – chaperone binds to exposed hydrophobic residues on unfolded protein

IV – folded protein is released