TLS Online TPP Program

#Question id: 1250


Few mutants (column A) and their results (column B) are listed in the table given below:

Column AColumn B
A. Gain-of-function of SkiI. Inhibits the ability of activated type I TGF-β receptors (RI) to phosphorylate R-Smad proteins
B. Loss-of-function of RII receptorII. Transcription activation induced by TGF-β and mediated by Smad complexes is shut down
C. Gain-of-function of smad-7
D. Loss-of-function of R-smad

Match the correct mutation with the observe result?

#Unit 4. Cell Communication and Cell Signaling
  1. A and D-II, B and C-I

  2. A and B-II, C and D-I

  3. A and B-I, C and D-II

  4. A and C-II, B and D-I