Pro-survival members-

Bcl-2, Bcl-xL, Bcl-w, Mcl-1, A1

TLS Online TPP Program

#Id: 6483

#Unit 3. Fundamental Processes

For RNA polymerase II, the positioning factor is TFIID, which consists of TBP associated with up to 14 other subunits called TAFs (for TBP -associated factors). 

TLS Online TPP Program

#Id: 4333

#Unit 1. Molecules and their Interaction Relevant to Biology

About 75% of the charged residues in proteins are members of ion pairs that are located mostly on the protein surface.

Despite the strong electrostatic attraction interactions contribute little to the stability of a native protein.

TLS Online TPP Program

#Id: 6308

#Unit 3. Fundamental Processes

RNA polymerase performs two proofreading functions on that growing transcript. 

The first of these is called pyrophosphorolytic editing. In this, the enzyme uses its active site, in a simple back-reaction, to catalyze the removal of an incorrectly inserted ribonucleotide, by reincorporation of PPi. The enzyme can then incorporate another ribonucleotide in its place in the growing RNA chain. Note that the enzyme can remove either correct or incorrect bases in this manner, but spends longer hovering over mismatches than matches, and thus removes the former more frequently.

TLS Online TPP Program

#Id: 7768

#Unit 1. Molecules and their Interaction Relevant to Biology

Atoms are indivisible particles that can't be created or destroyed in a chemical reaction.

TLS Online TPP Program

#Id: 6663

#Unit 3. Fundamental Processes