Nurturing Life Sciences
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Alternative Properdin-Activated Pathway
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#Unit 5. Developmental Biology
Nodal related low + Veg T, Vg1 = Ventral mesoderm
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The “default fate” of the ectoderm is to become neural tissue
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The ectoderm is induced to become epidermal tissue by BMPs
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#Id: 975
Noggin binds to BMP4 and BMP2 and inhibits their binding to receptors
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Siamois and Twin inducing the activation of the neuroepithelium genes –Foxd4 and Sox11