Core enzyme binds indiscriminately to any DNA. Sigma factor reduces the affinity for sequence independent binding and confers specificity for promoter.

TLS Online TPP Program

#Id: 1045

#Unit 5. Developmental Biology

The highly proliferative mesenchyme that fuels limb bud growth is known as the progress zone mesenchyme

TLS Online TPP Program

#Id: 6343

#Unit 8. Inheritance Biology

X-Linked Color Blindness in Humans 

The human eye perceives color through light-sensing cone cells that line the retina.  Each cone cell contains one of three pigments capable of absorbing light of a particular wavelength: one absorbs blue light, a second absorbs red light, and a third absorbs green light.

TLS Online TPP Program

#Id: 3297

#Unit 3. Fundamental Processes

oxoG:A repair, Oxidation of guanine produces oxoG. 

The modified base can be repaired before replication by DNA glycosylase via the base excision pathway. 

If replication occurs before the oxoG is removed, resulting in the misincorporation of an A, then a fail-safe glycosylase can remove the A, allowing it to be replaced by a C. 

This provides a second opportunity for the DNA glycosylase to remove the modified base.

TLS Online TPP Program

#Id: 10460

#Unit 4. Cell Communication and Cell Signaling

Burkitt’s lymphoma

translocation between chromosomes 8 and 14

TLS Online TPP Program

#Id: 7269

#Unit 6. System Physiology – Plant

The activity of rubisco is also regulated by light, but the enzyme itself does not respond to thioredoxin.

Two protons are released during the formation of the ternary complex rubisco–CO2–Mg2+, so activation is promoted by an increase in both pH and Mg2+ concentration.