The recognition sequences for Type II endonucleases form palindromes with rotational symmetry

TLS Online TPP Program

#Id: 6529

#Unit 7. System Physiology – Animal

Insulin has an AB heterodimer structure with 

One intrachain (A6-A11) 

Two interchain disulfide bridges (A7-B7 and A20-B19)

TLS Online TPP Program

#Id: 6530

#Unit 7. System Physiology – Animal

TLS Online TPP Program

#Id: 6531

#Unit 7. System Physiology – Animal

Insulin secretion by the pancreatic beta cells in response to increased blood glucose concentration

TLS Online TPP Program

#Id: 6532

#Unit 7. System Physiology – Animal

The beta cells have a large number of glucose transporters that permit a rate of glucose influx that is proportional to the blood concentration in the physiological range

TLS Online TPP Program

#Id: 6533

#Unit 7. System Physiology – Animal

The entry of glucose into pancreatic β cells is mediated by the GLUT2 glucose transporter Because the Km for glucose of GLUT2 is 20 mM, a rise in extracellular glucose from 5 mM, causes a proportional increase in the rate of glucose entry

TLS Online TPP Program

#Id: 6534

#Unit 7. System Physiology – Animal

The conversion of glucose into pyruvate is accelerated, resulting in an increase in the concentration of ATP in the cytosol