Pointers

  1. Home
  2. Free Resources
  3. Pointers
  4. 4016
TLS Online TPP Program

#Id: 4016

The nuclear matrix and chromosome scaffold consist of different proteins, although there are some common components. Topoisomerase II is a prominent component of the chromosome scaffold, and is a constituent of the nuclear matrix, suggesting that the control of topology is important in both cases.
SATB1, is a protein that appears to regulate the association of MARs with the matrix in order to regulate transcription of genes in the vicinity of the MAR.

#Unit 2. Cellular Organization #CELL CYCLE #Part B Pointers
PYQ Links
  1. PYQ 1
Extensive Links
  1. Link 1
More Pointers
TLS Online TPP Program

#Id: 8764

#Unit 1. Structure and Function of Biomolecules

Some thermostable proteins are stabilized by an increased size of the protein’s hydrophobic core, an increased size of the interface between its domains and/or subunits, and a more tightly packed core as evidenced by a reduced surface-to-volume ratio.
TLS Online TPP Program

#Id: 8765

#Unit 1. Structure and Function of Biomolecules

Disulfide bonds are believed to increase the stability of the native state by decreasing the conformational entropy of the unfolded state due to the conformational constraints imposed by cross-linking (i. e. decreasing the free energy of the unfolded state).  
TLS Online TPP Program

#Id: 8766

#Unit 1. Structure and Function of Biomolecules

Most protein have "loops" introduced by disulfides of about 15 residues
TLS Online TPP Program

#Id: 8767

#Unit 1. Structure and Function of Biomolecules

Guanidinium ion and urea are chaotropic agents which disrupts hydrophobic core of proteins.
TLS Online TPP Program

#Id: 8768

#Unit 1. Structure and Function of Biomolecules

TLS Online TPP Program

#Id: 8769

#Unit 1. Structure and Function of Biomolecules