Nurturing Life Sciences
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#Unit 5. Developmental Biology
The adult stem cell is housed in and controlled by its own adult stem cell niche, which regulates stem cell self-renewal, survival, and differentiation of those progeny that leave the niche.
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The somatic cells of the hub create asymmetric proliferation by secreting the paracrine factor Unpaired onto the cells attached to them
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Unpaired protein activates the JAK-STAT pathway in the adjacent germ stem cells to specify their self-renewal
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The mode of fertilization in sea urchin being external, the egg and spermatozoa are released into the sea water.