Mutations in dnaA render replication asynchronous, which suggests that DnaA could be the “titrator” or “clock” that measures the number of origins relative to cell mass.

TLS Online TPP Program

#Id: 6540

#Unit 7. System Physiology – Animal

The binding of insulin is communicated through the single TM helix of each beta subunit to the paired Tyr kinase domains inside the cell, activating them to phosphorylate each other on three Tyr residues (Tyr1158, Tyr1162, Tyr1163)

TLS Online TPP Program

#Id: 10288

#Unit 4. Cell Communication and Cell Signaling

TLS Online TPP Program

#Id: 9470

#Unit 4. Cell Communication and Cell Signaling

Phosphorylated STAT dissociates spontaneously from the receptor, and two phosphorylated STAT proteins form a homodimer.

TLS Online TPP Program

#Id: 7966

#Unit 2. Cellular Organization

Binding of BiP to the luminal domain of monomeric Ire1 prevents formation of the Ire1 dimer.

TLS Online TPP Program

#Id: 4752

#Unit 5. Developmental Biology

The P1 cell develops autonomously without the presence of AB, generating all the cells it would normally make, and the result is the posterior half of an embryo.