In DNA polymerase, the nucleotide-binding pocket cannot accommodate a 2’-OH on the in-coming nucleotide. This space is occupied by two amino acids that make van der Waals contacts with the sugar ring. Changing these amino acids to other amino acids with 

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#Id: 6108

#Unit 3. Fundamental Processes

In ames test reversal mutants are formed by same mutagen which caused forward mutation.

A more potent mutagen translates

into a greater number of revertant colonies

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#Unit 5. Developmental Biology

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#Id: 3853

#Unit 5. Developmental Biology

In D. discoideum cAMP phosphodiesterase RegA plays a crucial role in regulating intracellular cAMP levels cells & level of PKA activity.

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#Id: 8255

#Unit 1. Molecules and their Interaction Relevant to Biology

Potential energy of Dipole-Dipole Interaction

V is the potential energy

μ is the dipole moment

ϵo is the vacuum permittivity.

R is the length between the two nuclei

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#Unit 4. Cell Communication and Cell Signaling

p53 protein product is regulated by a protein called MDM2, which works through a negative feedback loop.