A new model for the structure of the DNA Pol III complex proposes a three-polymerase core structure, with two Pol III catalytic cores responsible for synthesis of the lagging strand and one for the leading strand.

TLS Online TPP Program

#Id: 3078

#Unit 3. Fundamental Processes

The rodlike shape ofthe bacterium is maintained by three proteins: MreB, PBP2, and RodA.

TLS Online TPP Program

#Id: 3079

#Unit 3. Fundamental Processes

The structure of MreB protein resembles that of the eukaryotic protein actin, which polymerizes to form cytoskeletal filaments in eukaryotic cells.

TLS Online TPP Program

#Id: 3080

#Unit 3. Fundamental Processes

In bacteria, MreB polymerizes and appears to move in patches around the circumference of the cell attached to the peptidoglycan synthesis machinery, includingPBP2.

TLS Online TPP Program

#Id: 3081

#Unit 3. Fundamental Processes

RodA is a member of the SEDS (shape, elongation, division, and sporulation) family present in all bacteria that have a peptidoglycan cell wall.

TLS Online TPP Program

#Id: 3082

#Unit 3. Fundamental Processes

fts mutants form long filaments because the septum that divides the daughter bacteria fails to form.

TLS Online TPP Program

#Id: 3083

#Unit 3. Fundamental Processes

Minicells form in mutants that produce too many septa; they are small and lack DNA.