The modified base can be repaired before replication by DNA glycosylase via the base excision pathway. If replication occurs before the oxoG is removed, resulting in the misincorporation of an A, then a fail-safe glycosylase can remove the A, allowing it to be replaced by aC. This provides a second opportunity for the DNA glycosylase to remove the modified base.

TLS Online TPP Program

#Id: 4637

#Unit 13. Methods in Biology

Caspases western blotting assay is also used to detect apoptosis

TLS Online TPP Program

#Id: 483

#Unit 2. Cellular Organization

Interphase chromosomes occupy chromosome territories in the nucleus and are not entangled with each other

TLS Online TPP Program

#Id: 2932

#Unit 3. Fundamental Processes

Replication in bacteria and in eukaryotes is licensed and permitted to occur only once per cell cycle.

TLS Online TPP Program

#Id: 8612

#Unit 2. Cellular Organization

Phosphorylation of a critical threonine residue in the activation loop, Thr-160, allowing substrates to access the active site of the CDK

TLS Online TPP Program

#Id: 1344

#Unit 4. Cell Communication and Cell Signaling

RAS is connected to the membrane by a prenylated (lipid) tail.