Mammalian fertilization occurs inside the oviducts  of the female

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#Id: 3288

#Unit 6. System Physiology – Plant

Complex IV, also called cytochrome oxidase, carries electrons from cytochrome c to molecular oxygen, For every four electrons passing through this complex, the enzyme consumes four “substrate” Hfrom the matrix (N side) in converting O2 to 2H2O

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#Unit 6. System Physiology – Plant

The overall reaction catalyzed by Complex IV is

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#Unit 6. System Physiology – Plant

Ubiquinone (Q) is reduced by four ways;

a. By the oxidation of NADH in complex I
b. Electrons from succinate pass through a flavoprotein with the cofactor FAD and several Fe-S
centers (in Complex II) on the way to Q
c. Glycerol 3-phosphate donates electrons to a flavoprotein (glycerol 3-phosphate dehydrogenase)
on the outer face of the inner mitochondrial membrane, from which they pass to Q.
d. Acyl-CoA dehydrogenase (the first enzyme of oxidation) transfers electrons to electron-
transferring flavoprotein (ETF), from which they pass to Q via ETF

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#Unit 6. System Physiology – Plant

Glycerol 3-phosphate shuttle
In the cytosol, dihydroxyacetone phosphate accepts two reducing equivalents from NADH in a reaction catalyzed by cytosolic glycerol 3-phosphate dehydrogenase

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#Unit 6. System Physiology – Plant

formation of ROS in two condition;
a) Mitochondria are not making ATP (for lack of ADP or O2) and therefore have a large proton-motive force and a high ratio of QH2/Q
b) there is a high NADH/NADratio in the matrix

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#Unit 6. System Physiology – Plant