The SRP and the nascent polypeptide chain–ribosome complex bind to the SRP receptor in the ER membrane. This interaction is strengthened by the binding of GTP to both the SRP and its receptor.

TLS Online TPP Program

#Id: 4476

#Unit 13. Methods in Biology

Differential-interference-contrast (DIC) microscopy based on splitting of light into two and then recombining them to observe their interference pattern.

TLS Online TPP Program

#Id: 4477

#Unit 13. Methods in Biology

DIC microscopy is used for visualizing extremely small details and thick objects.

TLS Online TPP Program

#Id: 4478

#Unit 13. Methods in Biology

DIC microscopy easily defines the outlines of large organelles, such as the nucleus and vacuole.

TLS Online TPP Program

#Id: 4479

#Unit 13. Methods in Biology

Formaldehyde a common fixative, crosslinks amino groups on adjacent molecules

TLS Online TPP Program

#Id: 4480

#Unit 13. Methods in Biology

Histological samples are often stained with hematoxylin and eosin (“H&E stain”).

TLS Online TPP Program

#Id: 4481

#Unit 13. Methods in Biology

Hematoxylin binds to basic amino acids (lysine and arginine).