Monogamy

Each individual mates exclusively with one partner over at least a single breeding cycle and sometimes for longer.

Monogamy occurs in fish, amphibians, reptiles, and mammals, but it is only commonly observed in birds, some rodents, and a few primate species.

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#Id: 9981

#Unit 4. Cell Communication and Cell Signaling

Delipidation process reduces Wnt signaling, creates a negative feedback mechanism for preventing excessive Wnt signaling.

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#Id: 9982

#Unit 4. Cell Communication and Cell Signaling

Frizzled receptor possesses a unique hydrophobic cleft adapted to interact with lipidated Wnts, a binding conformation mimicked in Notum’s structure as well.

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#Id: 9983

#Unit 4. Cell Communication and Cell Signaling

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#Id: 9984

#Unit 4. Cell Communication and Cell Signaling

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#Id: 9985

#Unit 4. Cell Communication and Cell Signaling

Antagonists of Wnt:

Secreted frizzled-related protein (Sfrp)

Wnt inhibitory factor (Wif)

Dickkopf (Dkk) family

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#Id: 9986

#Unit 4. Cell Communication and Cell Signaling

Non-canonical Wnt signaling is initiated by the 

Wnt5a type (Wnt4, Wnt5a, Wnt5b, Wnt6, Wnt7a, and Wnt11).