Scaffolds for MAP kinase pathways are well documented in yeast, fly, and worm cells, but their presence in mammalian cells has been difficult to demonstrate. Perhaps the best documented scaffold protein in metazoans is Ksr (kinase suppressor of Ras).

A. Ksr functions as a molecular scaffold by binding several signaling components of the MAP kinase cascade, including both MEK and MAP kinase; and thus can enhance MAP kinase activation by regulating the efficiency of these interactions.

B. Ksr function as a protein kinase which constitutive activate RTK signalling pathway.

C. Ksr function as a receptor proteins which inhibits RTK signalling pathway.

D. Ksr function as a protein phosphatase which inhibits RTK signalling pathway.

Which of the following statement is correct about Ksr?

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#Question id: 5064

#Unit 5. Developmental Biology

Fibroblast growth factors, epidermal growth factors, platelet-derived growth factors, and stem cell factor are all paracrine factors that bind to

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#Question id: 6575

#General Aptitude

Which term comes next in the sequence : AB, DEF, HIJK, ? , STUVWX

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#Question id: 12832

#General Aptitude

What is the area of dark (coloured) sector for the figure given below?

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#Question id: 9601

#Unit 9. Diversity of Life Forms

The relative lengths of the frog and mouse branches in the phylogenetic tree indicate that

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#Question id: 379

#Unit 1. Molecules and their Interaction Relevant to Biology

A compound has a pKa of 7.4. To 100 mL of a 1.0 M solution of this compound at pH 8.0 is added 30 mL of 1.0 M hydrochloric acid. The resulting solution is pH: