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TLS Online TPP Program

#Question id: 14969

 A new drug is developed that targets and binds to the lipid A portion of LPS from Gram negative bacterial cells. This drug shows a high degree of activity and binding in a test tube setting against purified lipid A. Based on this information,

#Unit 2. Cellular Organization
  1. We should fast track this drug and get it out to physicians immediately to help prevent toxic/septic shock in humans.
  2. We should do some animal testing with whole Gram-negative cells and the drug before we jump to any conclusions.
  3. We should next proceed by moving to testing in a test tube using whole Gram-negative cells to see if it binds with the same strength.
  4. We should abandon the drug entirely binding to lipid A won't kill the bacteria, so the drug is useless to develop further
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TLS Online TPP Program

#Question id: 28158

#Unit 1. Structure and Function of Biomolecules

competitive inhibition may be

a. linear

b. parabolic

c. hyperbolic

d. zig-zag
TLS Online TPP Program

#Question id: 28159

#Unit 1. Structure and Function of Biomolecules

The given plot and statement are made after performing the DST calorimetry of a protein

a. X represents perfect folding of protein

b. X represents breaking of a bond

c. Y represents perfect folding of protein

d. Y represents perfect breaking of a bond

Which of the following is correct
TLS Online TPP Program

#Question id: 28160

#Unit 1. Structure and Function of Biomolecules

'Protein folding is not random, must have pathways' this statement can be explained by
TLS Online TPP Program

#Question id: 28161

#Unit 1. Structure and Function of Biomolecules

In Parkinson disease, the misfolded form of the protein Alpha-synuclein aggregates into spherical filamentous masses called
TLS Online TPP Program

#Question id: 10970

#Unit 1. Structure and Function of Biomolecules

A mother of blood type A+ who has always been perfectly healthy just delivered her second child. The father is of blood group O−. Knowing that the child is of blood group O− (O, Rh−), what would you expect to find in this child?
TLS Online TPP Program

#Question id: 10413

#Unit 1. Structure and Function of Biomolecules

Following are certain statements are related to the effect of red and far-red light;
a) under a dense canopy much of the red light is absorbed by plant pigments, resulting in transmittance of mostly far-red light
b) Pr (red) has highest photon flux at 680 nm while Pfr (far-red) has highest photon flux at 730nm
c) Pfr far-red light–absorbing form, which is considered to be the physiologically active form of phytochrome
d) R:FR ratio is strongly affected by the presence of a canopy because chlorophyll absorbs far-red but not red light
Which one of the combinations of above statements is incorrect?