TLS Online TPP Program

#Question id: 15442


XIAP, one member of a family of inhibitor of apoptosis proteins (IAPs), provides another way to restrain both initiator and effector caspases; Find out the INCORRECT statements about this inhibitor-

#Unit 4. Cell Communication and Cell Signaling
  1. XIAP has three N-terminal BIR domains; 
  2.  BIR2 binds to and inhibits two effector caspases, caspase-3 and caspase-7
  3. BIR3 binds to and inhibits initiator caspase-9. 
  4. BIR 2 and BIR3 both inhibits casapase-9 only
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TLS Online TPP Program

#Question id: 30113

#Unit 1. Molecules and their Interaction Relevant to Biology

Aspartate (Asp) is an amino acid with the structure NH2-CH(CH2-COOH)COOH. Given below are biosynthetic processes occurring in cells:
A. protein synthesis
B. de novo synthesis of inosine monophosphate and orotic acid
C. synthesis of adenosine monophosphate from inosine monophosphate
D. glutathione synthesis

Which one of the following options correctly represents all the biosynthetic process( es) wherein Asp is involved as a precursor?

TLS Online TPP Program

#Question id: 30114

#Unit 1. Molecules and their Interaction Relevant to Biology

In the case of monoclonal antibody production by hybridoma technology, myeloma cells used lack the enzyme hypxanthine - guanine phosphoriboxyl transferase(HGPRT) such that fused cells can only survive when selected on hypoxanthine-aminopterinthymdine (HAT). What is the role of aminopterin in this medium?

TLS Online TPP Program

#Question id: 30115

#Unit 1. Molecules and their Interaction Relevant to Biology

The antibacterial trimethoprim is an inhibitor of 

TLS Online TPP Program

#Question id: 30115

#Unit 1. Molecules and their Interaction Relevant to Biology

The antibacterial trimethoprim is an inhibitor of 

TLS Online TPP Program

#Question id: 30116

#Unit 1. Molecules and their Interaction Relevant to Biology

During purine synthesis the activity of amidotransferase enzyme is inhibited by the antitumor agent, mark the correct one.

TLS Online TPP Program

#Question id: 30117

#Unit 1. Molecules and their Interaction Relevant to Biology

Catabolic end product of purines is