TLS Online TPP Program

#Question id: 179


The average molecular weight of the 20 standard amino acids is 138, but biochemists use 110 when estimating the number of amino acids in a protein of known molecular weight.  Why?

#Unit 1. Molecules and their Interaction Relevant to Biology
  1. The number 110 is based on the fact that the average molecular weight of a protein is 110,000 with an average of 1,000 amino acids.

  2. The number 110 reflects the higher proportion of small amino acids in proteins, as well as the loss of water when the peptide bond forms.

  3. The number 110 reflects the number of amino acids found in the typical small protein, and only small proteins have their molecular weight estimated this way.

  4. The number 110 takes into account the relatively small size of nonstandard amino acids.

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TLS Online TPP Program

#Question id: 3834

#Unit 3. Fundamental Processes

In his transformation experiments, what phenomenon did Griffith observe?

TLS Online TPP Program

#Question id: 3835

#Unit 3. Fundamental Processes

State whether the following statements is true/false regarding DNA replication.

1. A short primer is added to the DNA polymerase reaction mix for Sanger DNA sequencing that has a 5ʹ free hydroxyl to which new nucleotides can be added.

2. In a sequencing gel, all fragment in one of the four lanes terminates in the same type of nucleotide base.

3. Eukaryotic cells contain at least five DNA polymerases all of which are responsible for nuclear DNA replication.

4. Since the rate of form movement in eukaryotes is much slower than that of bacteria, chromosomes require more than an hour to replicate.

5. Although histones and DNA are made in the same parts of the eukaryotic cell, the packaging of them in the nucleosome slows down replication so that it is slower than that of prokaryotes.

TLS Online TPP Program

#Question id: 3836

#Unit 3. Fundamental Processes

Which of the following statements accurately describes the differences between DNA replication in prokaryotes and DNA replication in eukaryotes?

TLS Online TPP Program

#Question id: 3837

#Unit 3. Fundamental Processes

How does the enzyme telomerase meet the challenge of replicating the ends of linear chromosomes?

TLS Online TPP Program

#Question id: 3838

#Unit 3. Fundamental Processes

Which of the following statements correctly describes the difference between the leading and the lagging strands of DNA during DNA replication?

TLS Online TPP Program

#Question id: 3839

#Unit 3. Fundamental Processes

Use the figure to answer the following question. In the late 1950s, Meselson and Stahl grew bacteria in a medium containing "heavy" (radioactive) nitrogen (15N) and then transferred them to a medium containing 14N (nonradioactive). Which of the results in the figure would be expected after one round of DNA replication in the presence of 14N?