The sequences of the recombination sites recognized by site-specific recombinases are ____________

TLS Online TPP Program

#Question id: 2057

#Unit 4. Cell Communication and Cell Signaling

Lymph nodes and the spleen are the most highly organized secondary lymphoid organs. T-cell and B-cell activity are separated into distinct microenvironments in both. T cells and B cells  are found in

TLS Online TPP Program

#Question id: 2058

#Unit 4. Cell Communication and Cell Signaling

NOD-like receptors (NLRs) are a large family of cytosolic PRRs activated by intracellular PAMPs, DAMPs, and other harmful substances. The NOD NLRs bind intracellular microbial components such as cell wall fragments. NLRC family are NOD1 and NOD2 recognise?

TLS Online TPP Program

#Question id: 13159

#Unit 4. Cell Communication and Cell Signaling

How signaling is involved in ensuring that yeast cells fuse only with cells of the opposite mating type?

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#Question id: 13160

#Unit 4. Cell Communication and Cell Signaling

According to the Switching mechanism, monomeric G proteins exist in two states. Match the following states (Column I) with correct mechanism (Column II).

Column I	Column II
A. “ON” state	i. switch I and switch II, are bound to the terminal γ phosphate of GTP through interactions with the backbone amide groups of conserved threonine and glycine residues.
B. “OFF” state	ii. GTPase-activating proteins
	iii. guanine nucleotide exchange factor
	iv. Due to the removal of the γ phosphate by GTPase-catalyzed hydrolysis causes switch I and switch II to relax into a different conformation

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#Question id: 13161

#Unit 4. Cell Communication and Cell Signaling

Which of the following mechanism depends on the activation of heterotrimeric G proteins?

TLS Online TPP Program

#Question id: 13162

#Unit 4. Cell Communication and Cell Signaling

In the amoeba Dictyostelium discoideum, cAMP acts as an extracellular signalling molecule and binds to and signals via a G protein–coupled receptor; it is not a second messenger. Amoeba cells were transfected with genes encoding two fusion proteins: a Gα fused to cyan fluorescent protein (CFP), and a Gβ fused to yellow fluorescent protein (YFP). CFP normally fluoresces 490-nm light; YFP, 527-nm light. In which conditions fluorescence

energy transfer occur from CFP to YFP?