#Question id: 5236
#Unit 5. Developmental Biology
Following statements regarding to signaling pathways that control the properties of germline stem cells in drosophila.
A. The signaling molecules—the TGF-β-family proteins Dpp and Gbb as well as Hedgehog (Hh)—are maintain the self -renewal property of germline stem cells by the repression of differentiation factor.
B. Both E-cadherin and Arm are important in maintaining the germline stem-cell niche and regulate the proliferation of stem cells.
C. The signaling molecules—the TGF-β-family proteins Dpp and Gbb as well as Hedgehog (Hh)—are maintain germline stem cell
niche as well as self-renewal property.
D. Both E-cadherin and Arm are important in maintaining the self -renewal property of germline stem cells by the repression of differentiation factor.
Which of the following is correct?
#Question id: 5237
#Unit 5. Developmental Biology
Match the following stem cell type (Column I) with their niche location (Column II).
|
Column I |
Column II |
|
A. Intestine |
i. Bone marrow |
|
B. Hematopoietic stem cells |
ii. Bulge |
|
C. Hair follicle |
iii. Testes |
|
D. Sperm |
iv. Base of small intestinal crypts |
Which of the following is correct?
#Question id: 5238
#Unit 5. Developmental Biology
all tissue types possess a unique stem cell niche, and despite many differences among the niche architecture of different tissues, several common principles of stem cell regulation can be applied to all environments. These principles involve extracellular mechanisms leading to intracellular changes that regulate stem cell behavior.
|
Column A |
Column B |
|
I. Extracellular regulatory mechanisms |
i. Regulation by endocrine, paracrine, or juxtacrine mechanisms |
|
II. Intracellular regulatory mechanisms |
ii. Regulation by a network of transcription factors |
|
iii. Epigenetic regulation |
|
|
iv. Regulation by cell-to-cell and cell-to-matrix adhesions |
|
|
v. Regulation by cytoplasmic determinants |
Match the following regulatory mechanism (column A) with the factors that regulate stem cell behavior (column B).
#Question id: 5254
#Unit 5. Developmental Biology
Following signal transduction pathways can be grouped into several basic types, based on the sequence of intracellular events.
According to above figure, which of the following correctly represents the basic concepts of all signalling pathway?
#Question id: 14706
#Unit 5. Developmental Biology
Match the types of cell movement during gastrulation
#Question id: 14707
#Unit 5. Developmental Biology