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#Question id: 2897


The transcription of most protein coding genes in mammals (~70 percent) occurs at a lower rate than at TATA box–containing and initiator-containing promoters and begins at any of several alternative start sites within regions of about 100–1000 bp that have an unusually high frequency of CG sequences. Which one of the following best explains it?

#Unit 2. Cellular Organization
  1. CG-rich sequences are bound by histone octamers more tightly than CG-poor sequences because less energy is required to bend around the histone octamer forming a nucleosome.

  2. During housekeeping gene expression, the enzyme methyltransferase is temporarily silenced by miRNA, thus shutting down global methylation.

  3. As soon as the cytosine is methylated in the promoter region, the enzymes of DNA repair pathways remove the methyl group, thereby ensuring gene expression.

  4. A remarkable feature of the CpG islands is that transcription from these elements is initiated in both directions, even though only transcription of the sense strand yields an mRNA.

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TLS Online TPP Program

#Question id: 9162

#Unit 9. Diversity of Life Forms

If the direction of Earth's rotation reversed, the most predictable effect would be ________.

TLS Online TPP Program

#Question id: 16119

#Unit 7. System Physiology – Animal

Following statements are regarding to Shivering, which is the most potent mechanism for increasing heat production in the body. 
A. Cold environmental temperatures activate centers in the posterior hypothalamus during shivering, which then activate the α and γ motoneurons innervating skeletal muscle. 
B. Shivering involves skeletal muscle contracts rhythmically, generating heat and raising body temperature.
C. Shivering involves stimulation of Na+-K+ ATPase and raising body temperature.
D. Shivering involves stimulation of β receptors in brown fat, which increases metabolic rate and heat production.
Which of the following combination is correct?

TLS Online TPP Program

#Question id: 29491

#Unit 6. System Physiology – Plant

Which of the following is correctly matched with their  Response, phenomenon of photoreversibility and reciprocity 

TLS Online TPP Program

#Question id: 12831

#General Aptitude

The area of the triangle formed by the straight line 3x + 2y = 6 and the co-ordinate axes is

TLS Online TPP Program

#Question id: 15724

#Unit 11. Evolution and Behavior

Neo-Lamarckism includes several theories based on the old idea of inheritance of modifications acquired during an organism’s lifetime. In a famous experiment done by,