TLS Online TPP Program

#Question id: 3783


What is the basis for the difference in how the leading and lagging strands of DNA molecules are synthesized?

#Unit 3. Fundamental Processes
  1. The origins of replication occur only at the 5′ end.

  2. Helicases and single-strand binding proteins work at the 5′ end.

  3. DNA polymerase can join new nucleotides only to the 3′ end of a pre-existing strand, and the strands are antiparallel.

  4. DNA ligase works only in the 3′ → 5′ direction.

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TLS Online TPP Program

#Question id: 28795

#Unit 2. Cellular Organization

There are two major classes of actin-nucleating proteins:
I- Formins
II- Arp2/3 complex
a) nucleates the assembly of branched actin networks
b) landing site for profilin–ATP–G-actin
c) nucleate the assembly of unbranched filaments

Match the correct statements with ANPs-

TLS Online TPP Program

#Question id: 28796

#Unit 2. Cellular Organization

Formin family members have two adjacent domains such as;
I- FH1
II- FH2
a) form a nucleate filament assembly
b) rich in proline
c) form a dimer
d) landing site for profilin–ATP–G-actin
e) assembly of unbranched filaments

Match the correct statements with given formin family domain;

TLS Online TPP Program

#Question id: 28797

#Unit 2. Cellular Organization

Formins are activated by___

TLS Online TPP Program

#Question id: 28798

#Unit 2. Cellular Organization

To nucleate the assembly of branched actin filaments, Arp2/3 needs to be activated by___
a) Formins protein
b) nucleation promoting factor (NPF)
c) actin-nucleating proteins (ANP) 
d) Act A protein

TLS Online TPP Program

#Question id: 28799

#Unit 2. Cellular Organization

Arp2/3 needs to be activated by interacting with a nucleation promoting factor (NPF). Although there are many different NPFs, The major NPF family is characterized by the presence of a region called___

TLS Online TPP Program

#Question id: 28800

#Unit 2. Cellular Organization

Which type of signal is require to the activation of WASp, these signal input is called coincidence detection?
a) surface a protein ActA
b) regulatory phospholipid PIP2
c) small GTP-binding protein Rac1
d) small GTP-binding protein Cdc42