TLS Online TPP Program

#Question id: 3806


How are damaged nucleotides recognized by DNA repair enzymes?

#Unit 3. Fundamental Processes
  1. They are tagged with methyl groups.

  2. They are tagged with acetyl groups.

  3. They are recognized by their bulky geometry.

  4. They are recognized by lesion receptors.

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TLS Online TPP Program

#Question id: 12504

#Unit 8. Inheritance Biology

In this pedigree II 3 and III 1 are affected with an X-linked recessive disorder which is tightly linked to a marker locus with alleles A and B, with a recombination fraction of 0 between the disease and marker loci. Analysis of the linked marker results indicates that the disease must be segregating with:



TLS Online TPP Program

#Question id: 12505

#Unit 8. Inheritance Biology

The marker genotype for I 2 must have been:

TLS Online TPP Program

#Question id: 12506

#Unit 8. Inheritance Biology

Using the linked markers III 3 can be told that:

TLS Online TPP Program

#Question id: 12507

#Unit 8. Inheritance Biology

In this pedigree I 1 and II 2 have Becker muscular dystrophy which shows X-linked recessive inheritance. III 2 has oculocutaneous albinism which shows autosomal recessive inheritance with an incidence in the general population of 1 in 10 000. The disease status for both Becker muscular dystrophy and oculocutaneous albinism is unknown for IV 1 and IV 2.
What is the probability that III 3 is a carrier of Becker muscular dystrophy?


TLS Online TPP Program

#Question id: 12508

#Unit 8. Inheritance Biology

In this pedigree I 1 and II 2 have Becker muscular dystrophy which shows X-linked recessive inheritance. III 2 has oculocutaneous albinism which shows autosomal recessive inheritance with an incidence in the general population of 1 in 10 000. The disease status for both Becker muscular dystrophy and oculocutaneous albinism is unknown for IV 1 and IV 2.
What is the probability that III 3 is a carrier of oculocutaneous albinism?

TLS Online TPP Program

#Question id: 12509

#Unit 8. Inheritance Biology

In this pedigree I 1 and II 2 have Becker muscular dystrophy which shows X-linked recessive inheritance. III 2 has oculocutaneous albinism which shows autosomal recessive inheritance with an incidence in the general population of 1 in 10 000. The disease status for both Becker muscular dystrophy and oculocutaneous albinism is unknown for IV 1 and IV 2.
What is the probability that IV 1 is a carrier of oculocutaneous albinism?