TLS Online TPP Program

#Question id: 24478


Which of the following is incorrect order of binding of TBP

#Unit 3. Fundamental Processes
  1. In TATA – containing promoter first TBP bind and then binding of TAFs takes place
  2. In TATA less promoter with Inr and DPE  –  first TAFs binding takes place and then TBP bind
  3. In TATA less promoter with GC boxes – GC box recognizes Sp1 and Sp1 bind with TAFs and then bind of TBP takes place 
  4. In TATA less promoter with GC boxes – GC box recognizes  TAFs and TAFs bind with Sp1 and then bind of TBP takes place 
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TLS Online TPP Program

#Question id: 5802

#Unit 8. Inheritance Biology

A wild type allele:

TLS Online TPP Program

#Question id: 5803

#Unit 8. Inheritance Biology

The mutation which causes sickle cell anemia in humans:

TLS Online TPP Program

#Question id: 5804

#Unit 8. Inheritance Biology

The gene that is mutated in cases of cystic fibrosis encodes an ion transporter protein normally expressed in the respiratory and digestive tracts along with other locations. Individuals homozygous for the most common mutation in this gene (ΔF508) died at very early ages prior to the advent of advanced medical intervention. Despite this, the mutation exists at relatively high frequency in populations of European descent. One potential explanation is that heterozygotes for such mutations may be relatively immune to the lethal effects of diseases such as typhoid fever. Which statement below is most accurate?

TLS Online TPP Program

#Question id: 5805

#Unit 8. Inheritance Biology

In Himalayan rabbits, the ears, feet, and muzzle are pigmented while the rest of the body is white. This is because they express an enzyme variant that is ineffective at body temperature but functions at the lower temperatures experienced by cells of the extremities. This is an example of:

TLS Online TPP Program

#Question id: 5806

#Unit 8. Inheritance Biology

Which of these is NOT a mechanism by which a chromosome rearrangement could affect gene function?

TLS Online TPP Program

#Question id: 5807

#Unit 8. Inheritance Biology

Which of the following would be an example of a germline mutation?