Tay-Sachs disease belongs to the family of lysosomal storage diseases; it is an autosomal recessive neurodegenerative disorder caused by deficiency of the lysosomal enzyme hexosaminidase. The inability to degrade sphingolipids results in the deposition of these lipids in the cells that causes severe mental retardation and death in childhood. The most common mutation in Tay-Sachs disease patients is a 4-base pair insertion in exon 11 of the 14 exons of the hexosaminidase gene. What could be the most likely consequence of this mutation?

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#Question id: 4632

#Unit 11. Evolution and Behavior

Which of these conditions should completely prevent the occurrence of natural selection in a population over time?

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#Question id: 19809

#Unit 12. Applied Biology

For virus resistance many transgenic plants are produced by using which gene along with strong promoter?

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#Question id: 19788

#Unit 13. Methods in Biology

Thermal modulation are used in PCR for the function of__

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#Question id: 294

#Unit 1. Molecules and their Interaction Relevant to Biology

Which of the following pairs of amino acids would you predict to only participate in Van der Waals interactions in the three dimensional folding of a protein:

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#Question id: 1454

#Unit 4. Cell Communication and Cell Signaling

The human papillomavirus E7 protein inhibits the function of: