Tay-Sachs disease belongs to the family of lysosomal storage diseases; it is an autosomal recessive neurodegenerative disorder caused by deficiency of the lysosomal enzyme hexosaminidase. The inability to degrade sphingolipids results in the deposition of these lipids in the cells that causes severe mental retardation and death in childhood. The most common mutation in Tay-Sachs disease patients is a 4-base pair insertion in exon 11 of the 14 exons of the hexosaminidase gene. What could be the most likely consequence of this mutation?

#Question id: 10293

#Unit 6. System Physiology – Plant

the main glucose transporter in the cells of skeletal muscle, cardiac muscle, and adipose tissue, which is

#Question id: 10294

#Unit 6. System Physiology – Plant

Which of the following route are available for the oxidation of sugars in plant cells?

#Question id: 10295

#Unit 6. System Physiology – Plant

Reactions of the pentose phosphate pathway regeneration run six turns of this cycle, what will be predict after that?

#Question id: 10296

#Unit 6. System Physiology – Plant

Which of the following statements about the oxidative pentose phosphate pathway is incorrect?

#Question id: 10297

#Unit 6. System Physiology – Plant

The following statements are related to pentose phosphate pathway.

a) The first and third steps are oxidations with large, negative standard free-energy changes and are essentially irreversible in the cell

b) NADPH rises and inhibits the first enzyme in the pentose phosphate pathway. As a result, more glucose 6-phosphate is available for glycolysis

c) All the enzymes of the reversible reaction of the pentose phosphate pathway are located in the cytosol

d) The NADPH is used for biosynthetic reactions such as lipid synthesis and nitrogen assimilation in the cytosol

which one of the following combination  of above statements is incorrect?

#Question id: 10298

#Unit 6. System Physiology – Plant

Wernicke-Korsakoff syndrome is more common among people with alcoholism than in the general population, The syndrome can be exacerbated by a mutation in the gene for;