TLS Online TPP Program

#Question id: 4272


There are two classes of release factors for translation termination. Choose correct statements

A. Class I release factors recognize the stop codons and trigger hydrolysis of the peptide chain from the tRNA in the P-site.

B. Prokaryotes have two class I release factors called RF1 and RF2. RF1 recognizes the stop codon UGA, UAA and RF2 recognizes the stop codon UAG and UAA.

C. In eukaryotic cells, there is a single class I release factor called eRF1 that recognizes all three stop codons.

D. Class II release factors stimulate the dissociation of the ribosome after release of the polypeptide chain.

#Unit 3. Fundamental Processes
  1. A, B, & D only 

  2. A & C only

  3.  B & C only  

  4. A, B, C, & D only

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TLS Online TPP Program

#Question id: 4488

#Unit 3. Fundamental Processes

One component of thecomplex bears bromodomains and thus binds to acetylated nucleosomes better than to unacetylated nucleosomes. Thus, a gene bearing acetylated nucleosomes at its promoter will likely have a higher affinity for the transcriptional machinery than one with unacetylated nucleosomes.

TLS Online TPP Program

#Question id: 4489

#Unit 3. Fundamental Processes

HSP70 gene from Drosophila. This gene, activated by heat shock, is controlled by two activators GAGA binding factor and HSF,In response to heat shock, HSF binds to specific sites at the promoter and recruits a kinase, P-TEFb (positive transcription elongation factor). What is the proper mechanism of pausing and release of Pol II ?

TLS Online TPP Program

#Question id: 4490

#Unit 3. Fundamental Processes

The human immunodeficiency virus (HIV), which causes AIDS, transcribes its genes from a promoter controlled by P-TEFb (and SEC). Again, polymerase initiates transcription at that promoter, under the control of which activator?

TLS Online TPP Program

#Question id: 4491

#Unit 3. Fundamental Processes

HIV transcribes its genes from a promoter controlled by P-TEFb, P-TEFb is brought to the stalled polymerase by an RNA-binding protein, not a DNA-bound one. The protein responsible is called

TLS Online TPP Program

#Question id: 4492

#Unit 3. Fundamental Processes

If an enhancer activates a specific gene 400 kb away, what stops it from activating other genes whose promoters are within that range?

TLS Online TPP Program

#Question id: 4493

#Unit 3. Fundamental Processes

An insulator is placed between the enhancer and the promoter, When bound by insulator-binding protein CTCF,