Match the Following

A. fidelity of codon recognition	1. involves two adjacent adenine residues in the 16S rRNA component located within the A-site of the small subunit. These bases form hydrogen bonds with the minor groove of each correct base pair formed between the anticodon and the first two bases of the codon in the A-site
B. kinetic selectivity	2. Even a single mismatch in the codon–anticodon base pairing alters the position of EF-Tu, reducing its ability to interact with the factor-binding center. This, in turn, leads to a dramatic reduction in EF-Tu GTPase activity
C. Accommodation	3. When the charged tRNA is first introduced into the A-site in a complex with EF-Tu-GTP, its 30 end is distant from the site of peptide-bond formation. To participate successfully in the peptidyl transferase reaction, the tRNA must rotate into the peptidyl transferase center of the large subunit in a process

#Question id: 11079

#Unit 7. System Physiology – Animal

The diffusing capacity of a gas is the volume of gas that will diffuse through a membrane each minute for a pressure difference of 1 mm Hg. Which of the following gases is often used to estimate the oxygen diffusing capacity of the lungs?

#Question id: 11080

#Unit 7. System Physiology – Animal

The O2-CO2 diagram here shows a ventilation-perfusion ratio line for the normal lung. Which of the following best describes the effect of decreasing ventilation-perfusion ratio on the alveolar Po2 and Pco2?

#Question id: 11081

#Unit 7. System Physiology – Animal

In which of the following conditions is alveolar Po2 increased and alveolar Pco2 decreased?

#Question id: 11082

#Unit 7. System Physiology – Animal

A 67-year-old man has a solid tumor that pushes against an airway partially obstructing air flow to the distal alveoli. Which point on the ventilation-perfusion line of the O2-CO2 diagram corresponds to the alveolar gas of these distal alveoli?

#Question id: 11083

#Unit 7. System Physiology – Animal

A 55-year-old male has a pulmonary embolism that partially blocks the blood flow to his right lung. Which point on the ventilation-perfusion line of the O2-CO2 diagram corresponds to the alveolar gas of his right lung?

#Question id: 11084

#Unit 7. System Physiology – Animal

The next diagram shows two lung units (S and T) with their blood supplies. Lung unit S has an ideal relationship between blood flow and ventilation. Lung unit T has a comprised blood flow. What is the relationship between alveolar dead space (DALV), physiologic dead space (DPHY) and anatomic dead space (DANAT) for these lung units?